Wyss InstituteBrain Disease – Wyss Institute

Wyss Institute promotes Natalie Artzi to its Core Faculty and appoints Di Feng as an Associate Faculty member

Jessica Leff — Mon, 12 Aug 2024 13:15:25 +0000

By Benjamin Boettner (BOSTON) — Natalie Artzi, Ph.D., joined the ranks of the Wyss Institute’s now 12 Core Faculty members after only two years as an Associate Faculty member. Artzi’s promotion reflects her exceptional commitment to the Institute’s mission and the deep engagements and collaborations she has initiated within its technology development community. The Wyss Institute also warmly…

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Clarissa May Babila on Using “Packages” from Cells to Diagnose Brain Diseases

Jessica Leff — Mon, 29 Jul 2024 15:05:10 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. When Clarissa May Babila was in elementary school, there was one movie she wanted to watch over and over: a PBS documentary on Rosalind Franklin. That early love for science led her to an…

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Reimagining treatment for neurological diseases: Ayush Noori

Jessica Leff — Tue, 11 Jun 2024 15:09:44 +0000

By Jessica Leff Listen to Ayush tell his story | Wyss Institute · Ayush Noori Reimagine The World Ayush Noori grew up amidst a large extended family divided by geography – spread across California, Washington, and India – but united by shared core values of integrity, dedication, and resilience. At the center of this family was his grandmother, Munira Brooks, or as Ayush lovingly called…

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Brain Targeted Therapeutic Collaboration

Mariel Schoen — Mon, 25 Mar 2024 20:33:18 +0000

We actively collaborate with companies and academics to tailor our brain shuttles for drug delivery of specific payloads and diseases. Through extensive optimization of multiple shuttle-drug combinations in vitro and in vivo, we are developing safe and effective precision medicines for brain diseases. We provide a license and focused collaboration to aid company or academic collaborator in…

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Brain Shuttle Research Sponsorship & Licensing

Mariel Schoen — Mon, 25 Mar 2024 20:21:03 +0000

Brain Shuttles to TfR and CD98hc are available for licensing to sponsors Our antibody-fragment-based brain transport shuttles bind to proteins on the capillary side of human brain microvascular endothelial cells (BMECs), are transported through these cells, and are then released from the brain side of the capillaries, thereby efficiently crossing the blood brain barrier (BBB).

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Bridging the Funding Gap for Brain Therapeutics

Mariel Schoen — Mon, 25 Mar 2024 19:59:21 +0000

The Wyss Brain Targeting Program is uniquely positioned to catalyze therapeutic collaborations enabling development of innovative brain-targeted drugs. Our goal is to establish a center for brain-targeted therapeutic innovation. We envision a future in which chronic neurodegenerative diseases are preventable or treatable, and it is normal to remain high brain functioning throughout life.

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Liqun Wang on Delivering Drugs to the Brain

Jessica Leff — Tue, 28 Nov 2023 15:50:42 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Liqun Wang has always been fascinated by neuroscience. Early in her career, she did basic biomedical research to better understand a rare neurodegenerative disease called Alexander Disease.

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How can we better treat brain diseases?

Jessica Leff — Thu, 11 May 2023 15:41:33 +0000

The Brain Targeting Program at the Wyss Institute is a pre-competitive, multi-partner industry collaboration that aims to identify novel transport targets and shuttle compounds to enable more effective delivery of drugs to the brain. Credit: Wyss Institute at Harvard University…

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Reimagining treatment for brain diseases to improve the lives of patients and their families: Ana Raquel Santa Maria

Jessica Leff — Thu, 11 May 2023 15:05:21 +0000

By Jessica Leff Listen to Ana tell her story. | Wyss Institute · Ana Raquel Santa Maria Reimagine The World Situated in the eastern part of Beja, the second-most southern District of Portugal, Moura is a small, historic village with a dry climate, surrounded by a countryside full of oaks and olive trees. It’s where Ana Raquel Santa Maria, Ph.D, grew up with her mother, father…

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Tal Gilboa on Opening a Window into the Brain for Parkinson’s Diagnostics

Jessica Leff — Wed, 22 Feb 2023 15:54:46 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as scientists, and their collaborations at the Wyss Institute and beyond. As Tal Gilboa watched the condition of her mentor and family friend diagnosed with Parkinson’s disease rapidly decline early in her biomedical engineering studies, she longed to apply her skills…

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