Wyss InstituteLung Disease – Wyss Institute

Collaborative asthma project between Brigham and Women’s Hospital and the Wyss Institute advances with new grant support

Jessica Leff — Mon, 16 Dec 2024 15:55:41 +0000

By Benjamin Boettner (BOSTON) – Asthma affects more than 260M people worldwide and nearly 28M people in the U.S. alone, where, on average, 10 people die from attacks of the chronic disease each day. Many of these deaths could be prevented if patients had timely access to the appropriate therapy following an accurate diagnosis. Driven by an acute sense of urgency to close this diagnostic gap…

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Alex Plesa on Reversing Aging

Jessica Leff — Thu, 30 May 2024 13:00:18 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Most people believe that declining health as we age is an unfortunate, inevitable fact of life – but not Alex Plesa. He thinks the reason we think we can’t change it is because we don’t…

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The Wyss Institute’s 2024-2025 Validation Projects

Jessica Leff — Wed, 29 May 2024 14:55:23 +0000

Every year the Wyss Institute names a class of Validation Projects whose teams receive dedicated funding, business development support, and other resources to advance their promising technologies towards commercialization. They also collaborate with key opinion leaders, investors, and potential customers to de-risk their innovations and speed their progress to the market. This year…

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Emilia Javorsky on Finding Treatments for Radiation-Induced Lung Injury

Jessica Leff — Wed, 24 Jan 2024 14:00:59 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. While attending medical school, Emilia Javorsky realized how infrequently research actually becomes new, effective therapies for patients. So, she decided to pursue translational research…

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Erik Aznauryan on Curative Treatment of Genetic Diseases

Jessica Leff — Wed, 16 Aug 2023 13:40:30 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as scientists, and their collaborations at the Wyss Institute and beyond. Growing up with an ophthalmologist as a father, Erik Aznauryan’s interest in medicine began at a young age. Eventually, he realized that the scientific aspects of medicine interested him far…

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How do we make safer and more effective drugs?

Jessica Leff — Mon, 12 Jun 2023 15:14:20 +0000

Wyss researchers are using an ever-growing number of human tissue-mimicking Organ Chips to improve and accelerate the drug development process for a wide number of unmet diseases – and understand what causes them to erupt. More recently, they added a human Vagina Chip and personalized Barrett’s esophagus Chip to their arsenal, and created in vitro models of inflammatory bowel disease in children…

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Reimagine the World – Volume 2 – Diagnostics Accelerator

Jessica Leff — Tue, 18 Apr 2023 15:45:42 +0000

Two clinicians collaborating with the Wyss Diagnostics Accelerator (DxA), Lise Johnson and Craig Hersh, as well as two members of the Wyss DxA Industrial Partnership Program, Nell Meosky Luo and Andy Levin, share how they would Reimagine the World and the personal stories that fuel their passion for the work they are doing. Credit: Wyss Institute at Harvard University…

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Wyss researchers discover a new type of RNA that inhibits a broad range of viral infections

Jessica Leff — Wed, 05 Oct 2022 14:03:48 +0000

By Lindsay Brownell (BOSTON) — RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many types of non-living viruses, however, carry their genetic information in a double-stranded form of RNA (dsRNA). When the human immune system detects the presence of this foreign RNA, it sounds the alarm by increasing…

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Animal Free Labcast #4 – The Pioneer

Jessica Leff — Wed, 10 Aug 2022 15:18:50 +0000

World-class pioneer of biomedical research and innovation, Dr. Don Ingber, is the founding director of Harvard University’s Wyss Institute for Biologically Inspired Engineering. In 2010, Dr. Ingber developed a lung-on-a-chip – the first of its kind – and has continued to lead the field by developing numerous other organ chip models, demonstrating their ability to faithfully mimic human…

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Fighting viruses is as easy as breathing

Jessica Leff — Fri, 08 Apr 2022 09:00:57 +0000

By Lindsay Brownell (BOSTON) — The average person will take more than 600 million breaths over the course of their life. Every breath stretches the lungs’ tissues with each inhale and relaxes them with each exhale. The mere motions of breathing are known to influence vital functions of the lungs, including their development in babies, the production of air-exchange-enhancing fluid on their inner…

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