Wyss InstitutePersonalized Medicine – Wyss Institute

David Walt named as laureate for National Medal of Technology and Innovation

Jessica Leff — Tue, 07 Jan 2025 14:52:56 +0000

By Benjamin Boettner (BOSTON) — On January 3, Wyss Institute Core Faculty member David Walt, Ph.D., who also is a Professor of Pathology at Boston’s Brigham and Women’s Hospital (BWH), the Hansjörg Wyss Professor of Biologically Inspired Engineering at Harvard Medical School (HMS), an Associate member at the Broad Institute, and a Howard Hughes Medical Institute Professor…

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Collaborative asthma project between Brigham and Women’s Hospital and the Wyss Institute advances with new grant support

Jessica Leff — Mon, 16 Dec 2024 15:55:41 +0000

By Benjamin Boettner (BOSTON) – Asthma affects more than 260M people worldwide and nearly 28M people in the U.S. alone, where, on average, 10 people die from attacks of the chronic disease each day. Many of these deaths could be prevented if patients had timely access to the appropriate therapy following an accurate diagnosis. Driven by an acute sense of urgency to close this diagnostic gap…

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Wyss Institute’s iNodes team receives ARPA-H Sprint for Women’s Health award to advance the first implantable immune organs to treat ovarian cancer

Jessica Leff — Tue, 12 Nov 2024 14:58:41 +0000

By Benjamin Boettner (BOSTON) — Ovarian cancer is more deadly than any other type of female reproductive organ cancer. It is estimated that in 2024, in the U.S. alone, more than 12,000 women will die from the disease because available therapies are not effective. To help overcome this striking deficit in women’s health, ARPA-H has selected a team at the Wyss Institute at Harvard University as…

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Closing in on Parkinson’s Disease proteins in extracellular vesicles in the blood

Jessica Leff — Fri, 01 Nov 2024 13:20:38 +0000

By Benjamin Boettner (BOSTON) — Brain disorders like Parkinson’s (PD) or Alzheimer’s Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages. Thus far, the specific brain lesions…

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3D-printed blood vessels bring artificial organs closer to reality

Jessica Leff — Wed, 07 Aug 2024 16:55:18 +0000

By Lindsay Brownell (BOSTON) — Growing functional human organs outside the body is a long-sought “holy grail” of organ transplantation medicine that remains elusive. New research from Harvard’s Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engineering and Applied Science (SEAS) brings that quest one big step closer to completion. A team of scientists…

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A model of Collaborative Ethics to guide translational research from fundamental discoveries to real-world applications

Jessica Leff — Tue, 25 Jun 2024 14:55:06 +0000

By Benjamin Boettner (BOSTON) — In sciences, disruptive research that is breaking new ground often raises new and not-yet-explored ethical questions. Although new scientific breakthroughs can have the power to change how we understand and live in the world, the ethical implications of technologies that will emerge based on these new insights can affect an emerging field’s public acceptance and…

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ReConstruct: Vascularized tissue for breast reconstruction and augmentation

Seth Kroll — Wed, 01 May 2024 10:23:28 +0000

Breast cancer, the most common cancer worldwide, affects nearly 15% of all women. Most of these women undergo some kind of mastectomy to treat their cancer, and 40% choose to have breast reconstruction surgery. However, all currently available reconstruction options come with significant health risks. Artificial implants, whether filled with silicone or saline, require frequent safety monitor and…

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Cracking the code to precise and efficient gene editing with HarborSite

Jessica Leff — Mon, 18 Mar 2024 13:59:23 +0000

By Jessica Leff On October 15, 2019, two researchers joined the lab of Core Faculty member George Church, Ph.D., at the Wyss Institute. One, Tina Lebar, Ph.D., came from Slovenia to begin a postdoctoral fellowship. The other, Erik Aznauryan, Ph.D., was a visiting Ph.D. student studying in Switzerland. The two got to know each other as they went through lab tours, safety training…

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DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy

Jessica Leff — Fri, 15 Mar 2024 11:00:37 +0000

By Benjamin Boettner (BOSTON) — Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading. Multiple therapeutic cancer vaccines are being studied in clinical trials, but despite their promise, they are not routinely used yet by clinical oncologists to treat their patients.

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Reimagine the World – Volume 4 – ReConstruct Edition

Jessica Leff — Tue, 12 Mar 2024 13:41:49 +0000

Denise Skok, a two-time breast cancer survivor, Luba Perry, a scientist at the Wyss Institute, and Samuel Lin, a plastic surgeon collaborating with the Wyss Institute, are all working to reimagine a world where breast cancer patients have better reconstruction options. The ReConstruct project at the Wyss Institute uses adipose tissue assembled from a patient’s own cells and integrated into their…

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