Wyss InstituteComputer Science – Wyss Institute

From Data to Drugs: The Role of Artificial Intelligence in Drug Discovery

Jessica Leff — Thu, 09 Jan 2025 14:00:56 +0000

Code to Cure is a newsletter co-hosted by the Wyss Institute at Harvard University and Milad Alucozai on the intersection of AI, biology, and healthcare transforming medicine. By Milad Alucozai, Will Fondrie, and Megan Sperry Traditional drug discovery is slow, expensive, and prone to high clinical failure rates due to poor safety profiles, lack of efficacy, or both. Developing a new drug…

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From Bits to Biology: A New Era of Biological Renaissance powered by AI

Jessica Leff — Tue, 08 Oct 2024 13:00:59 +0000

Code to Cure is a newsletter co-hosted by the Wyss Institute at Harvard University and Milad Alucozai on the intersection of AI, biology, and healthcare transforming medicine. By Milad Alucozai Imagine a world where algorithms predict the next pandemic before it strikes, where you receive custom-designed treatments tailored to your individual genetic makeup, lifestyle, and medical history…

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Wyss Institute and Dr. Milad Alucozai Launch “Code to Cure” Newsletter

Jessica Leff — Tue, 17 Sep 2024 20:30:32 +0000

(BOSTON) – The Wyss Institute at Harvard University, along with Milad Alucozai, MSc, MPH, DrPH, is excited to announce the launch of the “Code to Cure” newsletter. Co-hosted by Alucozai and the Wyss Institute, this series will explore the convergence of artificial intelligence (AI), biology, and healthcare, highlighting the technologies and innovations shaping the future of human and planetary…

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AminoX: Making Better Protein Drugs, Quicker and Cheaper

Jessica Leff — Wed, 10 Jul 2024 13:56:00 +0000

A synthetic biology and advanced chemistry platform that efficiently incorporates non-standard amino acids by hacking the ubiquitous protein synthesis process. Credit: Wyss Institute at Harvard University…

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AminoX: Making Better Protein Drugs, Quicker and Cheaper

Jessica Leff — Wed, 01 May 2024 15:40:43 +0000

Protein drugs often offer the most effective way to treat a variety of medical illnesses and conditions. However, many proteins in their naturally occurring forms make poor drugs – they can cause toxicities that force patients to discontinue treatment, and they often have such short half-lives that patients would need to receive a constant infusion of them to see a therapeutic effect. Recently…

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Using AI, researchers identify a new class of antibiotic candidates

Jessica Leff — Wed, 20 Dec 2023 15:55:21 +0000

By Anne Trafton, MIT News Office Using a type of artificial intelligence known as deep learning, researchers at the Wyss Institute and MIT have discovered a class of compounds that can kill a drug-resistant bacterium that causes more than 10,000 deaths in the United States every year. In a study appearing today in Nature, the researchers showed that these compounds could kill methicillin…

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Coming together to engineer new treatments for serious diseases

Jessica Leff — Mon, 23 Oct 2023 17:14:48 +0000

By Jessica Leff Immunotherapy is often seen as the next frontier in cancer treatment, offering many benefits over traditional therapies like radiation and chemotherapy. Unfortunately, immunotherapy patients frequently experience painful side effects because antibodies affect healthy tissues along with the tumor. What if these drugs could more accurately target cancer cells…

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Now, every biologist can use machine learning

Jessica Leff — Wed, 21 Jun 2023 15:57:35 +0000

By Lindsay Brownell (BOSTON) — The amount of data generated by scientists today is massive, thanks to the falling costs of sequencing technology and the increasing amount of available computing power. But parsing through all that data to uncover useful information is like searching for a molecular needle in a haystack. Machine learning (ML) and other artificial intelligence (AI) tools can…

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Not all statins are created equal

Jessica Leff — Tue, 09 May 2023 14:58:02 +0000

By Lindsay Brownell (BOSTON) — We’ve all recently gotten a crash-course in drug repurposing, thanks to near-daily news reports about efforts to identify existing medicines that could help treat COVID-19 in the early phase of the pandemic. A team of scientists at the Wyss Institute at Harvard University jumped into the fray in the spring of 2020, applying novel computational drug repurposing…

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Giving old drugs new life…to save lives

Jessica Leff — Thu, 24 Feb 2022 15:00:32 +0000

By Lindsay Brownell (BOSTON) – Along with “SARS-CoV-2” and “cytokine storm,” the COVID-19 pandemic has added an alphabet soup of strange drug names to the public lexicon: hydroxychloroquine, tocilizumab, ivermectin, atovaquone. Though many of us were hearing those names (and struggling to spell them) for the first time, all of these drugs have been around for decades. It was our global…

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