Wyss InstituteMechanical Engineering – Wyss Institute

Gozde Basara on Engineering Safer Solutions for Cancer Survivors

Jessica Leff — Wed, 20 Nov 2024 16:22:50 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Gozde Basara has never shied away from learning something new. From starting a Ph.D. in 3D Bioprinting as a mechanical engineer with no advanced knowledge of biology to taking on new artistic…

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Hani Sallum on Engineering Prototypes for Researchers, Patients, and the Planet

Jessica Leff — Wed, 30 Oct 2024 13:00:46 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Hani Sallum is always tinkering, whether he’s creating an eight-foot-tall robot costume to show off at a convention or designing a carbon dioxide-powered seawater collection system to…

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Human cervix modeled in microfluidic organ chip fills key women’s health gap

Jessica Leff — Fri, 31 May 2024 14:55:29 +0000

By Benjamin Boettner (BOSTON) — Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women’s health and affects more than 25% of reproductive-aged women. It is caused by pathogenic bacteria that push the healthy microbiomes in the female vagina and cervix – the small gatekeeper canal that connects the uteruns and vagina – into a state of imbalance known as dysbiosis.

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Repairing patients’ dura more durably

Jessica Leff — Wed, 20 Mar 2024 17:55:14 +0000

By Benjamin Boettner (BOSTON) — The dural membrane (dura) is the outermost of three meningeal layers that line the central nervous system (CNS), which includes the brain and spinal cord. Together, the meninges function as a shock-absorber to protect the CNS against trauma, circulate nutrients throughout the CNS, as well as remove waste. The dura also is a critical biological barrier that…

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A new glue, potentially also for you

Jessica Leff — Tue, 20 Feb 2024 15:50:09 +0000

By Benjamin Boettner (BOSTON) — Hydrogels are versatile biomaterials conquering an increasing number of biomedical areas. Consisting of water-swollen molecular networks that can be tailored to mimic the mechanical and chemical features of various organs and tissues, they can interface within the body and on its outer surfaces without causing any damage to even the most delicate parts of the…

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Soft robotic, wearable device improves walking for individual with Parkinson’s disease

Jessica Leff — Fri, 05 Jan 2024 14:21:45 +0000

By Leah Burrows / SEAS Communications (CAMBRIDGE, Mass.) — Freezing is one of the most common and debilitating symptoms of Parkinson’s disease, a neurodegenerative disorder that affects more than 9 million people worldwide. When individuals with Parkinson’s disease freeze, they suddenly lose the ability to move their feet, often mid-stride, resulting in a series of staccato stutter steps that…

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Tunable ECMs for more effective T cell therapies

Jessica Leff — Mon, 11 Dec 2023 15:40:55 +0000

Adoptive immune cell therapies (ICTs) are taking their place in the pantheon of modern medicines alongside drugs and gene therapies. In ICTs, immune cells are taken out of patients and engineered and amplified in vitro act as “living drugs” that recognize and respond to disease states when infused back into patients. Multiple engineered T cell therapies, with so-called CAR-T cell therapies at the…

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Reimagining personalized medicine for each patient: Alican Ozkan

Jessica Leff — Thu, 07 Dec 2023 16:00:51 +0000

By Jessica Leff Listen to Alican tell his story. | Wyss Institute · Alican Ozkan Reimagine The World On the banks of the Aegean Sea sits Izmir, the third-most-populous city in Turkey. It’s geographically part of Asia, but culturally seems more at home in Europe. This is also the city where Alican Ozkan grew up. His parents, both chemical engineers, met at their university.

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Fiber-infused ink enables 3D-printed heart muscle to beat

Jessica Leff — Tue, 08 Aug 2023 14:30:44 +0000

By Kat J. McAlpine / SEAS Communications (BOSTON) – Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures. Their goals include creating better in vitro platforms for discovering new therapeutics for heart disease, the leading cause of death in the United States, responsible for about one in every five deaths…

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Wyss Institute promotes Christopher Chen to a Core Faculty member and appoints Ellen Roche and Michael Springer as new members of its Associate Faculty

Jessica Leff — Mon, 31 Jul 2023 14:58:15 +0000

By Benjamin Boettner (BOSTON) — Christopher Chen, M.D., Ph.D. has had a long and prolific past at the Wyss Institute and its 3D Organ Engineering Initiative as an Associate Faculty member, and based on his deep commitment to the Institute and its translational mission, he has now been promoted to become one of the Institute’s 12 Core Faculty members. The Wyss Institute is also excited to welcome…

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