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From Data to Drugs: The Role of Artificial Intelligence in Drug Discovery

Jessica Leff — Thu, 09 Jan 2025 14:00:56 +0000

Code to Cure is a newsletter co-hosted by the Wyss Institute at Harvard University and Milad Alucozai on the intersection of AI, biology, and healthcare transforming medicine. By Milad Alucozai, Will Fondrie, and Megan Sperry Traditional drug discovery is slow, expensive, and prone to high clinical failure rates due to poor safety profiles, lack of efficacy, or both. Developing a new drug…

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David Walt named as laureate for National Medal of Technology and Innovation

Jessica Leff — Tue, 07 Jan 2025 14:52:56 +0000

By Benjamin Boettner (BOSTON) — On January 3, Wyss Institute Core Faculty member David Walt, Ph.D., who also is a Professor of Pathology at Boston’s Brigham and Women’s Hospital (BWH), the Hansjörg Wyss Professor of Biologically Inspired Engineering at Harvard Medical School (HMS), an Associate member at the Broad Institute, and a Howard Hughes Medical Institute Professor…

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A Year in Review: 2024

Jessica Leff — Thu, 26 Dec 2024 14:00:20 +0000

By Jessica Leff In 2024, the Wyss community turned our new “house” at 201 Brookline Avenue into a “home,” filling the space with fun memories, innovative technologies, and our dedication to making a positive impact. We celebrated many milestones, from the completion of the inaugural Wyss Mentorship cohort to the first successful organ transplant from a pig donor, where the modified kidney was…

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Researchers call for global discussion about possible risks from “mirror bacteria”

Jessica Leff — Wed, 18 Dec 2024 14:27:15 +0000

A group of researchers including Wyss Core Faculty member George Church, Ph.D. has published new findings in Science on potential risks from the development of mirror bacteria — synthetic organisms in which all molecules have reversed chirality (i.e. are ‘mirrored’). Scientists had begun early work toward creating mirror bacteria, and while the capability is at least a decade away…

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Collaborative asthma project between Brigham and Women’s Hospital and the Wyss Institute advances with new grant support

Jessica Leff — Mon, 16 Dec 2024 15:55:41 +0000

By Benjamin Boettner (BOSTON) – Asthma affects more than 260M people worldwide and nearly 28M people in the U.S. alone, where, on average, 10 people die from attacks of the chronic disease each day. Many of these deaths could be prevented if patients had timely access to the appropriate therapy following an accurate diagnosis. Driven by an acute sense of urgency to close this diagnostic gap…

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Innovative tissue engineering: ESCAPE, a pioneering new method explained

Jessica Leff — Wed, 11 Dec 2024 16:00:31 +0000

By Boston University Communications (BOSTON) — When it comes to the human body, form and function work together. The shape and structure of our hands enable us to hold and manipulate things. Tiny air sacs in our lungs called alveoli allow for air exchange and help us breath in and out. And tree-like blood vessels branch throughout our body, delivering oxygen from our head to our toes.

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Gozde Basara on Engineering Safer Solutions for Cancer Survivors

Jessica Leff — Wed, 20 Nov 2024 16:22:50 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Gozde Basara has never shied away from learning something new. From starting a Ph.D. in 3D Bioprinting as a mechanical engineer with no advanced knowledge of biology to taking on new artistic…

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Wyss Institute’s iNodes team receives ARPA-H Sprint for Women’s Health award to advance the first implantable immune organs to treat ovarian cancer

Jessica Leff — Tue, 12 Nov 2024 14:58:41 +0000

By Benjamin Boettner (BOSTON) — Ovarian cancer is more deadly than any other type of female reproductive organ cancer. It is estimated that in 2024, in the U.S. alone, more than 12,000 women will die from the disease because available therapies are not effective. To help overcome this striking deficit in women’s health, ARPA-H has selected a team at the Wyss Institute at Harvard University as…

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Closing in on Parkinson’s Disease proteins in extracellular vesicles in the blood

Jessica Leff — Fri, 01 Nov 2024 13:20:38 +0000

By Benjamin Boettner (BOSTON) — Brain disorders like Parkinson’s (PD) or Alzheimer’s Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages. Thus far, the specific brain lesions…

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Hani Sallum on Engineering Prototypes for Researchers, Patients, and the Planet

Jessica Leff — Wed, 30 Oct 2024 13:00:46 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Hani Sallum is always tinkering, whether he’s creating an eight-foot-tall robot costume to show off at a convention or designing a carbon dioxide-powered seawater collection system to…

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