Wyss InstituteDiagnostics Accelerator – Wyss Institute

Collaborative asthma project between Brigham and Women’s Hospital and the Wyss Institute advances with new grant support

Jessica Leff — Mon, 16 Dec 2024 15:55:41 +0000

By Benjamin Boettner (BOSTON) – Asthma affects more than 260M people worldwide and nearly 28M people in the U.S. alone, where, on average, 10 people die from attacks of the chronic disease each day. Many of these deaths could be prevented if patients had timely access to the appropriate therapy following an accurate diagnosis. Driven by an acute sense of urgency to close this diagnostic gap…

Source

Clarissa May Babila on Using “Packages” from Cells to Diagnose Brain Diseases

Jessica Leff — Mon, 29 Jul 2024 15:05:10 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. When Clarissa May Babila was in elementary school, there was one movie she wanted to watch over and over: a PBS documentary on Rosalind Franklin. That early love for science led her to an…

Source

Innovating Diagnostics to Improve Clinical Care and Patient Outcomes

Jessica Leff — Wed, 15 May 2024 17:46:59 +0000

Guest speaker, Sarah-Beth Perullo, shares the immense difficulty she faced in obtaining a diagnosis for her mysterious symptoms. Her story is a sobering reminder of how frequent patient symptoms are dismissed in the medical field. Credit: Wyss Institute at Harvard University…

Source

Instrument-Free Molecular Diagnostics

Mariel Schoen — Wed, 01 May 2024 17:25:23 +0000

Molecular diagnostics is the fastest-growing segment of the global in vitro diagnostics market, but the vast majority of these tests require expensive equipment and supplies, limiting their use to medical facilities. There is a large unmet need for cheap, readily accessible, accurate diagnostic tests that can be deployed in non-clinical settings to address threats to public health…

Source

Paper-Based Diagnostics

admin — Wed, 01 May 2024 00:34:41 +0000

With the imminent threat of new pandemics and frequent disease outbreaks exemplified by the recent Ebola and Zika epidemics, there is a growing need for low-cost, easily deployable and simple-to-use diagnostic tools. The Wyss Institute has developed paper-based synthetic gene networks as a next generation diagnostic technology for use in global healthcare crises and patient care. This new type of…

Source

Bogdan Budnik on Analyzing Proteins to Develop Better Diagnostics and Therapeutics

Jessica Leff — Thu, 15 Feb 2024 14:50:30 +0000

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. After studying physics for many years, Bogdan Budnik realized instead of using his knowledge to generate power, he wanted to use it to empower people with better disease diagnostics and…

Source

Extracellular Vesicles for Biomarker Detection

Mariel Schoen — Wed, 24 Jan 2024 22:09:57 +0000

The Walt lab has developed an assay and platform to collect novel biomarkers in the form of extracellular vesicles (EVs) released from cells. As a result, a wider variety of EVs with unmatched quality, quantity, and purity can be obtained. EVs hold incredible value for the scientific and medical communities, as they can provide a better understanding of how disease starts in organs and tissues…

Source

Announcing the 2024 “Faculty Focus” List

Mariel Schoen — Wed, 24 Jan 2024 22:05:49 +0000

This year, we’re excited to announce our first-ever Wyss Faculty Focus list. We asked our world-class faculty which of their technologies they’re most excited about getting out of the lab and into the real world, and they’ve chosen the ones below. If you’re interested in collaborating, licensing, or otherwise getting involved with any of these technologies, please reach out to their respective…

Source

Changing the calculus of cancer treatment

Jessica Leff — Wed, 24 Jan 2024 22:04:52 +0000

This year’s American Cancer Society’s cancer statistics report revealed that despite falling rates of some cancers over the last few decades, the incidence of breast, prostate, oral cavity, melanoma, and kidney cancers has been rising in recent years. Most concerningly, colorectal cancer has jumped to become the leading cause of cancer deaths in adults under 50. Despite the strides made by new…

Source

Brigham-Wyss DxA

Mariel Schoen — Tue, 31 Oct 2023 18:01:32 +0000

The Wyss DxA’s clinical partners from Brigham and Women’s Hospital identify the most pressing unmet diagnostic needs, provide access to high-quality patient samples for our Biomarker Discovery Laboratory (BDL) and Brigham-Wyss DxA collaborators, and provide invaluable feedback and guidance on the engineering and validation of cost-effective, sensitive, and specific diagnostic tests.

Source