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		<title>Wyss InstituteImmuno-Materials &#8211; Wyss Institute</title>
		<link>https://wyss.stage.a17.io</link>
		<description>Wyss Institute at Harvard</description>
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				<title>Injectable Hydrogel Adhesive for Improved Muscle Regeneration</title>
				<link>https://wyss.stage.a17.io/technology/injectable-hydrogel-adhesive-for-improved-muscle-regeneration/</link>
        <pubDate>Wed, 06 Nov 2024 14:30:59 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[David J. Mooney]]></category>
		<category><![CDATA[Harvard SEAS]]></category>
		<category><![CDATA[Hydrogel]]></category>
		<category><![CDATA[Muscle]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?post_type=technology&#038;p=41422</guid>
                                                <content:encoded><![CDATA[<p>Although it was only given a clinical definition in 2010, volumetric muscle loss (VML) has been a persistent problem in medicine for centuries. VML can be caused by injuries, diseases, and some surgical procedures like removing a tumor, and results in so much damage to a muscle that its function is permanently compromised, leading to long&#x2d;term disability. There is currently no effective treatment&#8230;</p>
<p><a href="https://wyss.stage.a17.io/technology/injectable-hydrogel-adhesive-for-improved-muscle-regeneration/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/technology/injectable-hydrogel-adhesive-for-improved-muscle-regeneration/</link>
          <title>This scanning electron microscopy (SEM) image of the hydrogel displays its crosslinked microstructure that allows it to maintain its shape while stretching and moving with muscle tissue. Credit: Wyss Institute at Harvard University</title>
					<url>https://wyss-stage.imgix.net/app/uploads/2024/11/04164330/20241104-Hydro-Gel-SEM_Gold-copy.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=e35db66357893cddd92ca18aa07f8b56"/></url>
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				<title>Kwasi Adu-Berchie named 2024 STAT Wunderkind</title>
				<link>https://wyss.stage.a17.io/news/kwasi-adu-berchie-named-2024-stat-wunderkind/</link>
        <pubDate>Wed, 16 Oct 2024 14:11:12 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Awards]]></category>
		<category><![CDATA[Community]]></category>
		<category><![CDATA[Biological Materials]]></category>
		<category><![CDATA[David J. Mooney]]></category>
		<category><![CDATA[Malaria]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=41197</guid>
                            <description>The honor is bestowed annually on the next generation of scientific superstars</description>
                                        <content:encoded><![CDATA[<p>By Lindsay Brownell (BOSTON) &ndash; The Wyss Institute is thrilled to announce that Kwasi Adu&#x2d;Berchie, Ph.D., a member of the Wyss&rsquo; Advanced Technology Team working in Immuno&#x2d;Materials Platform led by Core Faculty member Dave Mooney, Ph.D., has been named a 2024 STAT Wunderkind by STAT News. The Wunderkinds awards are given annually by STAT News to the next generation of scientific superstars who&#8230;</p>
<p><a href="https://wyss.stage.a17.io/news/kwasi-adu-berchie-named-2024-stat-wunderkind/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/kwasi-adu-berchie-named-2024-stat-wunderkind/</link>
          <title>Kwasi Adu-Berchie</title>
					<url>https://wyss-stage.imgix.net/app/uploads/2022/08/10092956/Kwasi-Adu-Berchie-3.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=4a6a7501c813f36b02821b455fa1d73c"/></url>
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				<title>Attivare licenses Wyss Institute’s immune-modulating biomaterial technology to advance immunotherapies</title>
				<link>https://wyss.stage.a17.io/news/attivare-licenses-wyss-institutes-immune-modulating-biomaterial-technology-to-advance-immunotherapies/</link>
        <pubDate>Wed, 02 Oct 2024 13:20:13 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Press Releases]]></category>
		<category><![CDATA[Translation News]]></category>
		<category><![CDATA[Biomedical Engineering]]></category>
		<category><![CDATA[Blood]]></category>
		<category><![CDATA[Dana-Farber Cancer Institute]]></category>
		<category><![CDATA[David J. Mooney]]></category>
		<category><![CDATA[Harvard SEAS]]></category>
		<category><![CDATA[Immune System]]></category>
		<category><![CDATA[Massachusetts General Hospital]]></category>
		<category><![CDATA[Technology Translation]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=41088</guid>
                            <description>The startup is leveraging the biomaterial-based technology to develop novel therapies able to program anti-cancer immunity and prevent infectious diseases</description>
                                        <content:encoded><![CDATA[<p>By Benjamin Boettner (BOSTON) &mdash; Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Attivare Therapeutics Inc. announced that Attivare has licensed a portfolio of immune&#x2d;modulating biomaterial technologies from Harvard University that was created at the Wyss Institute, John A. Paulson School of Engineering and Applied Sciences (SEAS)&#8230;</p>
<p><a href="https://wyss.stage.a17.io/news/attivare-licenses-wyss-institutes-immune-modulating-biomaterial-technology-to-advance-immunotherapies/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/attivare-licenses-wyss-institutes-immune-modulating-biomaterial-technology-to-advance-immunotherapies/</link>
          <title> The OMNIVAX infection vaccine approach incorporates pathogen-derived antigens into an injectable biomaterial scaffold which presents them together with immune cell attracting and activating factors to dendritic immune cells that then go on to orchestrate multi-faceted immune responses against the pathogen in nearby lymph nodes. Credit: Wyss Institute at Harvard University</title>
					<url>https://wyss-stage.imgix.net/app/uploads/2020/05/20143742/MPS-Scaffold-SEM-001-e1590000157764.jpeg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=b22cd283948c2a998b8ada8474c9e03f"/></url>
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				<title>Vinny Chandran Suja on Making Backpacks More Reliable and Predictable</title>
				<link>https://wyss.stage.a17.io/news/humans-of-the-wyss-vinny-chandran-suja-on-making-backpacks-more-reliable-and-predictable/</link>
        <pubDate>Tue, 20 Aug 2024 13:10:41 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Community]]></category>
		<category><![CDATA[Brain]]></category>
		<category><![CDATA[Brain Disease]]></category>
		<category><![CDATA[Brain Health]]></category>
		<category><![CDATA[Brain Injury]]></category>
		<category><![CDATA[Humans of the Wyss]]></category>
		<category><![CDATA[Immune System]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[Nanoparticles]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=40839</guid>
                                                <content:encoded><![CDATA[<p>The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. As a kid, Vinny Chandran Suja had no interest in biology. Instead, his math and science acumen led him to pursue degrees in mechanical and chemical engineering, studying non&#x2d;living systems.</p>
<p><a href="https://wyss.stage.a17.io/news/humans-of-the-wyss-vinny-chandran-suja-on-making-backpacks-more-reliable-and-predictable/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/humans-of-the-wyss-vinny-chandran-suja-on-making-backpacks-more-reliable-and-predictable/</link>
          <title>Vinny Chandran Suja, Postdoctoral Fellow. Credit: Wyss Institute at Harvard University </title>
					<url>https://wyss-stage.imgix.net/app/uploads/2024/08/19095508/HoW-Vinny-Suja-04607.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=bdf61545789ef6d11eb055eb87b90950"/></url>
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				<title>Wyss Institute promotes Natalie Artzi to its Core Faculty and appoints Di Feng as an Associate Faculty member</title>
				<link>https://wyss.stage.a17.io/news/wyss-institute-promotes-natalie-artzi-to-its-core-faculty-and-appoints-di-feng-as-an-associate-faculty-member/</link>
        <pubDate>Mon, 12 Aug 2024 13:15:25 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Community]]></category>
		<category><![CDATA[Press Releases]]></category>
		<category><![CDATA[Beth Israel Deaconess Medical Center]]></category>
		<category><![CDATA[Biomedical Engineering]]></category>
		<category><![CDATA[Brain]]></category>
		<category><![CDATA[Brigham and Women's Hospital]]></category>
		<category><![CDATA[Di Feng]]></category>
		<category><![CDATA[Harvard Medical School]]></category>
		<category><![CDATA[Natalie Artzi]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=40759</guid>
                            <description>Artzi’s promotion and Feng’s appointment strengthen the Institute’s efforts in nanomedicine and immunoengineering, as well as modeling of chronic kidney diseases</description>
                                        <content:encoded><![CDATA[<p>By Benjamin Boettner (BOSTON) &mdash; Natalie Artzi, Ph.D., joined the ranks of the Wyss Institute&rsquo;s now 12 Core Faculty members after only two years as an Associate Faculty member. Artzi&rsquo;s promotion reflects her exceptional commitment to the Institute&rsquo;s mission and the deep engagements and collaborations she has initiated within its technology development community. The Wyss Institute also warmly&#8230;</p>
<p><a href="https://wyss.stage.a17.io/news/wyss-institute-promotes-natalie-artzi-to-its-core-faculty-and-appoints-di-feng-as-an-associate-faculty-member/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/wyss-institute-promotes-natalie-artzi-to-its-core-faculty-and-appoints-di-feng-as-an-associate-faculty-member/</link>
          <title>In August, we announced <a href="https://wyss.harvard.edu/news/wyss-institute-promotes-natalie-artzi-to-its-core-faculty-and-appoints-di-feng-as-an-associate-faculty-member/">Natalie Artzi’s promotion to Core Faculty member and the appointment of Di Feng</a> as an Associate Faculty member. Credit: Wyss Institute at Harvard University</title>
					<url>https://wyss-stage.imgix.net/app/uploads/2024/08/08145256/ArtziFengComposite.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=1c298d6dde25ec80aa1f9fe30f99b0fd"/></url>
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				<title>Justin Scott on Engineering Proteins for Real-World Impact</title>
				<link>https://wyss.stage.a17.io/news/justin-scott-on-engineering-proteins-for-real-world-impact/</link>
        <pubDate>Wed, 26 Jun 2024 15:05:06 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Community]]></category>
		<category><![CDATA[Humans of the Wyss]]></category>
		<category><![CDATA[Protein Engineering]]></category>
		<category><![CDATA[Women's Health]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=40307</guid>
                                                <content:encoded><![CDATA[<p>The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and beyond. Years ago, Justin Scott was working in finance when a conversation with a friend who cared deeply about their science&#x2d;related job prompted him to make a change. Chasing that same job&#8230;</p>
<p><a href="https://wyss.stage.a17.io/news/justin-scott-on-engineering-proteins-for-real-world-impact/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/justin-scott-on-engineering-proteins-for-real-world-impact/</link>
          <title>Justin Scott, Scientist I. Credit: Wyss Institute at Harvard University</title>
					<url>https://wyss-stage.imgix.net/app/uploads/2024/06/26110347/HoW-Justin-Scott-00632.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=c502c3ee1f93bff7f6a959414ada24d9"/></url>
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				<title>Boosting CAR-T cell therapies from under the skin</title>
				<link>https://wyss.stage.a17.io/news/boosting-car-t-cell-therapies-from-under-the-skin/</link>
        <pubDate>Wed, 12 Jun 2024 13:15:07 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Press Releases]]></category>
		<category><![CDATA[Biomaterials]]></category>
		<category><![CDATA[Biomedical Engineering]]></category>
		<category><![CDATA[David J. Mooney]]></category>
		<category><![CDATA[Harvard SEAS]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=40215</guid>
                            <description>T-cell stimulating biomaterial that slowly biodegrades under the skin stimulates CAR-T cells in the body to improve therapeutic efficacy in an aggressive mouse tumor model</description>
                                        <content:encoded><![CDATA[<p>By Benjamin Boettner (BOSTON) &mdash; CAR&#x2d;T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR&#x2d;T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway. However, according to a recent study out of the Massachusetts General Hospital, among 100 patients suffering from lymphomas, myelomas or B&#x2d;cell&#8230;</p>
<p><a href="https://wyss.stage.a17.io/news/boosting-car-t-cell-therapies-from-under-the-skin/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/boosting-car-t-cell-therapies-from-under-the-skin/</link>
          <title></title>
					<url>https://wyss-stage.imgix.net/app/uploads/2024/06/11130643/CAR-T-cells-in-TES_Listing-Image.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=f8d3347264b06fc101ad4c5b0d6b9f00"/></url>
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				<title>Expanding a lymph node, boosting a vaccine</title>
				<link>https://wyss.stage.a17.io/news/expanding-a-lymph-node-boosting-a-vaccine/</link>
        <pubDate>Mon, 06 May 2024 09:15:39 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Press Releases]]></category>
		<category><![CDATA[Biomaterials]]></category>
		<category><![CDATA[Biomedical Engineering]]></category>
		<category><![CDATA[Cancer Vaccine]]></category>
		<category><![CDATA[David J. Mooney]]></category>
		<category><![CDATA[Gene Expression]]></category>
		<category><![CDATA[Harvard SEAS]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=39890</guid>
                            <description>A biomaterial vaccine enhances and sustains lymph node expansion following vaccination, boosting anti-tumor immunity in an animal model</description>
                                        <content:encoded><![CDATA[<p>By Benjamin Boettner (BOSTON) &mdash; Each one of us has around 600 lymph nodes (LNs) &ndash; small, bean&#x2d;shaped organs that house various types of blood cells and filter lymph fluid &ndash; scattered throughout our bodies. Many of us have also experienced some of our LNs to temporarily swelling during infections with viruses or other pathogens. This LN expansion and subsequent contraction can also result from&#8230;</p>
<p><a href="https://wyss.stage.a17.io/news/expanding-a-lymph-node-boosting-a-vaccine/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/expanding-a-lymph-node-boosting-a-vaccine/</link>
          <title>This immunofluorescent staining shows a lymph node that has been significantly expanded in mice with the help of the biomaterial MPS-vaccine (on the right), next to a lymph node taken from non-treated control mice (on the left) at the same time post-vaccination. Credit: Wyss Institute at Harvard University</title>
					<url>https://wyss-stage.imgix.net/app/uploads/2024/05/01142936/lymph-node-staining-001.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=ca5c0dcbfb6b24c6b94244fb5015a90b"/></url>
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				<title>Metabolically Labeled CAR-T Cells Against Cancer</title>
				<link>https://wyss.stage.a17.io/technology/metabolically-labeled-car-t-cells-against-cancermetabolic-t-cell-labeling-enhancing-t-cells-therapeutic-potential-with-immune-stimulating-cytokines/</link>
        <pubDate>Wed, 01 May 2024 17:03:45 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[David J. Mooney]]></category>
		<category><![CDATA[Harvard SEAS]]></category>
		<category><![CDATA[Immune System]]></category>
		<category><![CDATA[Metabolic Engineering]]></category>
		<category><![CDATA[Nanoparticles]]></category>
		<category><![CDATA[Northpond]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?post_type=technology&#038;p=35590</guid>
                                                <content:encoded><![CDATA[<p>In recent years, adoptive T cell therapies like CAR&#x2d;T cell therapy &ndash; in which T cells are obtained from a patient, genetically enhanced ex vivo, and infused back into the same patient &ndash; have shown spectacular success in the treatment of blood cancers, including leukemias, lymphomas, and more lately multiple myelomas. However, not all patients with a given blood cancer benefit equally from this&#8230;</p>
<p><a href="https://wyss.stage.a17.io/technology/metabolically-labeled-car-t-cells-against-cancermetabolic-t-cell-labeling-enhancing-t-cells-therapeutic-potential-with-immune-stimulating-cytokines/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/technology/metabolically-labeled-car-t-cells-against-cancermetabolic-t-cell-labeling-enhancing-t-cells-therapeutic-potential-with-immune-stimulating-cytokines/</link>
          <title></title>
					<url>https://wyss-stage.imgix.net/app/uploads/2023/02/03105032/listing-image-Metabolic-T-Cell.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=1aa53488e7a3bf1a3e5c517dccaff876"/></url>
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				<title>Repairing patients’ dura more durably</title>
				<link>https://wyss.stage.a17.io/news/repairing-patients-dura-more-durably/</link>
        <pubDate>Wed, 20 Mar 2024 17:55:14 +0000</pubDate>
        <dc:creator><![CDATA[Jessica Leff]]></dc:creator>
        		<category><![CDATA[Press Releases]]></category>
		<category><![CDATA[Biomedical Engineering]]></category>
		<category><![CDATA[Brain]]></category>
		<category><![CDATA[Brain Injury]]></category>
		<category><![CDATA[Brigham and Women's Hospital]]></category>
		<category><![CDATA[David J. Mooney]]></category>
		<category><![CDATA[Harvard SEAS]]></category>
				<guid isPermaLink="false">https://wyss.harvard.edu/?p=39492</guid>
                            <description>Highly adhesive and mechanically strong Dural Tough Adhesive addresses multiple limitations in the repair of the dural membrane lining the brain and spinal cord after trauma and surgeries</description>
                                        <content:encoded><![CDATA[<p>By Benjamin Boettner (BOSTON) &mdash; The dural membrane (dura) is the outermost of three meningeal layers that line the central nervous system (CNS), which includes the brain and spinal cord. Together, the meninges function as a shock&#x2d;absorber to protect the CNS against trauma, circulate nutrients throughout the CNS, as well as remove waste. The dura also is a critical biological barrier that&#8230;</p>
<p><a href="https://wyss.stage.a17.io/news/repairing-patients-dura-more-durably/" rel="nofollow">Source</a></p>]]></content:encoded>
                                    
				<image>
          <link>https://wyss.stage.a17.io/news/repairing-patients-dura-more-durably/</link>
          <title>A research collaboration of bioengineers and neurosurgeons has developed a new solution to re-sealing the dura that, using a multi-functional biomaterial, addresses key limitations of current repair methods. Credit: Peter Allen, Ryan Allen, and James C. Weaver. SEAS/MIT/Wyss</title>
					<url>https://wyss-stage.imgix.net/app/uploads/2024/03/19161756/Dural-Tough-Adhesive-on-Brain-Tissue.jpg?auto=format%2Ccompress&#038;crop=faces%2Centropy&#038;fit=crop&#038;h=400&#038;q=50&#038;w=300&#038;s=4ee342604151b7e167b293e746f51219"/></url>
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