Wyss InstituteDisease Model – Wyss Institute

Innovative tissue engineering: ESCAPE, a pioneering new method explained

Jessica Leff — Wed, 11 Dec 2024 16:00:31 +0000

By Boston University Communications (BOSTON) — When it comes to the human body, form and function work together. The shape and structure of our hands enable us to hold and manipulate things. Tiny air sacs in our lungs called alveoli allow for air exchange and help us breath in and out. And tree-like blood vessels branch throughout our body, delivering oxygen from our head to our toes.

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ESCAPE Bioengineering

Jessica Leff — Wed, 11 Dec 2024 16:00:06 +0000

A research team at the Wyss Institute and Boston University has developed ESCAPE, the first method that enables the engineering of tissues across multiple length scales, ranging from the diameter of a cell to the cm scale of a heart valve. Credit: Wyss Institute at Harvard University…

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Wyss Institute’s iNodes team receives ARPA-H Sprint for Women’s Health award to advance the first implantable immune organs to treat ovarian cancer

Jessica Leff — Tue, 12 Nov 2024 14:58:41 +0000

By Benjamin Boettner (BOSTON) — Ovarian cancer is more deadly than any other type of female reproductive organ cancer. It is estimated that in 2024, in the U.S. alone, more than 12,000 women will die from the disease because available therapies are not effective. To help overcome this striking deficit in women’s health, ARPA-H has selected a team at the Wyss Institute at Harvard University as…

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Wyss Institute promotes Natalie Artzi to its Core Faculty and appoints Di Feng as an Associate Faculty member

Jessica Leff — Mon, 12 Aug 2024 13:15:25 +0000

By Benjamin Boettner (BOSTON) — Natalie Artzi, Ph.D., joined the ranks of the Wyss Institute’s now 12 Core Faculty members after only two years as an Associate Faculty member. Artzi’s promotion reflects her exceptional commitment to the Institute’s mission and the deep engagements and collaborations she has initiated within its technology development community. The Wyss Institute also warmly…

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Boosting CAR-T cell therapies from under the skin

Jessica Leff — Wed, 12 Jun 2024 13:15:07 +0000

By Benjamin Boettner (BOSTON) — CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway. However, according to a recent study out of the Massachusetts General Hospital, among 100 patients suffering from lymphomas, myelomas or B-cell…

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Reimagining treatment for neurological diseases: Ayush Noori

Jessica Leff — Tue, 11 Jun 2024 15:09:44 +0000

By Jessica Leff Listen to Ayush tell his story | Wyss Institute · Ayush Noori Reimagine The World Ayush Noori grew up amidst a large extended family divided by geography – spread across California, Washington, and India – but united by shared core values of integrity, dedication, and resilience. At the center of this family was his grandmother, Munira Brooks, or as Ayush lovingly called…

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Human cervix modeled in microfluidic organ chip fills key women’s health gap

Jessica Leff — Fri, 31 May 2024 14:55:29 +0000

By Benjamin Boettner (BOSTON) — Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women’s health and affects more than 25% of reproductive-aged women. It is caused by pathogenic bacteria that push the healthy microbiomes in the female vagina and cervix – the small gatekeeper canal that connects the uteruns and vagina – into a state of imbalance known as dysbiosis.

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The Wyss Institute’s 2024-2025 Validation Projects

Jessica Leff — Wed, 29 May 2024 14:55:23 +0000

Every year the Wyss Institute names a class of Validation Projects whose teams receive dedicated funding, business development support, and other resources to advance their promising technologies towards commercialization. They also collaborate with key opinion leaders, investors, and potential customers to de-risk their innovations and speed their progress to the market. This year…

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Mice Don’t Menstruate: Reimagining Women’s Health Using Organ Chips with Dr. Donald Ingber

Jessica Leff — Wed, 08 May 2024 13:05:03 +0000

In this episode, host Sharon Kedar, Co-Founder of Northpond Ventures, is joined by Dr. Donald Ingber, Founding Director at Wyss Institute for Biologically Inspired Engineering at Harvard University. Dr. Ingber’s commitment to following his passion has led him to countless medical and technological breakthroughs, including Organ Chip technology. These incredible chips recreate the structure and…

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Expanding a lymph node, boosting a vaccine

Jessica Leff — Mon, 06 May 2024 09:15:39 +0000

By Benjamin Boettner (BOSTON) — Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies. Many of us have also experienced some of our LNs to temporarily swelling during infections with viruses or other pathogens. This LN expansion and subsequent contraction can also result from…

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